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In the in vitro study comparing Restanza to azithromycin, Restanza showed two to ten-fold higher efficacy against Plasmodium falciparum with the IC50 and IC90 amounts, respectively, ranging from 0.2 to 2.7 and 0.6 to 6.2 ug/mL, of chloroquine susceptibility regardless. Especially, in the in vivo study, Restanza showed 100 percent efficacy in dealing with mice infected with Plasmodium berghei and was around three-fold more potent than azithromycin at fifty % of the same dosage..Molecular Characterization Partial sequences were obtained from the first isolated virus strain DBM, and the complete genomes of 11 additional individual isolates of SFTSV were identified. All isolates including stress DBM were closely related . The terminals of the three genomic segments of SFTSV had been found to be similar to counterparts in other phleboviruses.8 The L segment contains 6368 nucleotides with one open reading frame encoding 2084 proteins. The M segment consists of 3378 nucleotides with one open reading frame encoding 1073 amino acid precursors of glycoproteins .

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