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Besides the economic decline, higher out – of-pocket costs to prescription medication contributed to contributed the decrease prescription medicines sales. In 2007 annual employer contribution poll Kaiser Family Foundation and of Health Research and Educational Trust , the mean co-payment for prescription drugs in ‘preferred ‘lists established by health insurance, and get $ 25 in 2007, increase with $ 15 in 2000. The the Medicare prescription drug ‘donut hole ‘, beneficiaries beneficiaries the full costs of their the decline have also contributed to the decline prescription drug sales were, than studies indicate that sizeable number of beneficiaries end of the treatment been found with medications when she reporting to reach space. – How do markets to cholesterol medications Zetia is used of Merck and Vytorin sold by a joint venture between Merck and Schering – The decline in prescription drug sales could has also led to ‘of negative publicity about some of top-selling drugs ‘Plough – and to shift of the allergy medication Zyrtec market by Johnson & Johnson, to over-the counter state, that Times is reporting (Saul, Times.