So when we used statistical solutions to adjust for variations in age, the difference in oxygen amounts between African-Americans and Caucasians became more significant. Then, when we managed for racial differences, we discovered that increased age group became an important indicator of elevated oxygen levels in certain locations in leading section of the eye. A previously published research by Siegfried and co-workers demonstrated that oxygen amounts increase in the eye following vitrectomy, the surgery of the vitreous gel – a clear, jelly-like structure in the relative back of the attention – which is performed for a variety of retinal conditions.A blinded review of the info by the info and safety monitoring panel considered the outcomes from the first 443 enrolled patients, with 30-day survival data designed for 300 patients, on December 21, 2004. Based on this review, an random recommendation was made to discontinue enrollment of asystolic individuals because of an exceptionally low 30-time survival price in this subgroup . The analysis protocol was then amended accordingly. The number of patients to be enrolled was risen to 1300 to keep up the power of the analysis after a rise of 15 percent in the expected survival price in the placebo group.