By neutralizing GM-CSF reduced the HuCAL-based antibody MOR103 undesired proliferation and activation of inflammatory granulocytes and in several pathophysiological pathways in several pathophysiological pathways. More information and pictures can be found here.. The HuCAL-based antibody MOR103 targets GM-CSF treated as a means to treat inflammatory diseases such as psoriasis, multiple sclerosis , chronic obstructive pulmonary disease , asthma, and especially RA. The granulocyte-macrophage colony stimulating factor stimulates stem cells to produce granulocytes, and macrophages, and subsequently activates these differentiated immune cells. GM-CSF is part of the natural immune system and the inflammatory cascade, does not intend to focal point for inflammation in autoimmune dysregulation as RA to an increased production of pro-inflammatory cytokines, chemokines and proteases and thereby ultimately leading to the destruction been identified.
Kaiser Family Foundation. 2005 Advisory Board Company and Kaiser Family Foundation. All rights reserved.. About MorphoSysMorphoSys is a publicly traded biotechnology company specializing focused on developing fully human antibodies to discover and innovative antibody-based drugs against life-threatening diseases. Membrane, calledorphoSys is active in which establish HuCAL. As a technology of choice for antibody generation in research, diagnostics and therapeutic applications The company currently has. Therapeutic and research alliances with the majority of the world largest pharmaceutical companies, including Boehringer Ingelheim, Centocor / Johnson & Johnson, Novartis, Pfizer and Roche These partnerships are more than 50 therapeutic antibody programs MorphoSys am through exclusive license and milestones payments as well as royalties on any end products Additionally, MorphoSys is active in the antibody research market through its AbD Serotec business unit.Be hopes Davis said his the Team are the review of the literature a renewed a renewed exploring by biologists found in to the variety headgear both in the living room and fossil species.
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