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The Pivotal study design was a non-inferiority research with ankle fusion as the control. In a non-inferiority study, the primary objective is to demonstrate that a new treatment is equivalent to a standard therapy in regards to to a particular result while also having benefits for additional clinical end points, producing the brand new treatment an appealing option thus. Three sets of patients were used in the study: several 158 STAR total ankle sufferers and a control band of 66 ankle fusion individuals another band of 448 STAR individuals , whose surgery was performed following completion of enrollment in the Pivotal Study. Related StoriesNo progression in joint damage in 84 percent of psoriatic arthritis patientsACR releases 2015 Guideline for Treatment of Rheumatoid ArthritisImmune program protein has potential to prevent onset of aggressive type of rheumatoid arthritisResults were reported up to two years following surgery.