The compound, SU11248 or SUTENT, works to inhibit the growth of arteries that feed tumors also to halt cell reproduction by interfering with two receptors on the surface of tumor cells, said Kathy Miller, M.D., assistant professor of medication at the Indiana University College of Medication. Miller. The clinical trial involved 64 women with advanced disease who had not taken care of immediately other treatments. Early results for about 15 % of trial participants indicate no progression of the condition or at least a 50 % decrease in the size of their tumors. Miller. The drug, which is manufactured by Pfizer Oncology, will be further tested in a Phase III trial for patients with advanced disease and a Phase II trial of additional tumor types..Toxicity from restoration components Dental care amalgam fillings can release mercury, tin, copper, and silver into the physical body. These metals have several degrees of toxicity, and when utilized as fillings for tooth, can corrode or disassociate into metallic ions. These ions then migrate from the tooth to the main, the mouth area, the bone, the connective tissues of the jaw, and lastly into the nerves. This allows them to travel in to the central nervous system, where in fact the ions will reside permanently, disrupting the body’s normal functioning if they are not eliminated. While all metals used for dental restoration are toxic, the most dangerous are mercury dental amalgams used for fillings.